第六届超高压生物科学与技术国际会议闭幕

第六届超高压生物科学与技术国际会议闭幕第六届超高压生物科学与技术国际会议于2010年8月28日至9月1日在德国慕尼黑北部的弗赖辛召开。来自德国、法国、英国、西班牙、美国、加拿大、比利时、葡萄牙、苏格兰、匈牙利、波兰、科索沃、立陶宛、亚美尼亚、日本、印度、巴西、新西兰、中国等世界各地100多名从事超高压生物科学与技术的专家与学者聚集一堂，对“高压敏感分子的机制、高分子与高压加工、小分子与高压加工、高压敏感有机系统、深海生物、高压加工食品微生物学、高压加工对人类的影响、高压技术、高压技术分析”等学术问题发表论文并进行了热烈讨论。会议由德国慕尼黑理工大学RudyF.Vogel教授主持，日本近畿大学的KazuyukiAkasaka教授做了主题报告“HighPressureNMRStudyofProteins-SeekingRootsforFunction,Evolution,DiseaseandFoodApplications”。除了发表论文外，会场还有几十块展板，发表了论文摘要。我国首次出席这样的国际会议，郑捷代表天津科技大学食品学院刘安军院长、天津华泰森淼公司总工程师贾培起等五位参加研究的人员发表了论文“Superhighpressureeffectsonpropertiesandultrastructureofbeef（高压对牛肉蒸煮损失和组织结构的影响研究）”受到与会者的关注。会议决定第七届超高压生物科学与技术国际会议与2012年在日本举行，会议主持人为KazuyukiAkasaka教授。会场外景 会议主会场郑捷老师做报告 与会议主席Rudy（中）合影，左：贾培起，右：郑捷LectureprogramSaturday,August28,2010From14:00Receptionopen-Postermounting17:00Opening/Welcome,RudiF.VogelIntroductoryLectureChair:RudiF.Vogel17:15HighPressureNMRStudyofProteins-SeekingRootsforFunction,Evolution,DiseaseandFoodApplicationsKazuyukiAkasaka,KinkiUniversity,Kinokawa,JapanLI119:00WelcomereceptionSunday,August29,2010CHAPTER1:HighpressuresensitivemolecularmechanismsSession1:MacromoleculesandHHPChair:LazloSmellerandPhilOger08:30KEYNOTELECTURE:Thephysicalbasisforpressureeffectsonproteinstructureandstability.CatherineRoyer.INSERMCentredeBiochimieStructurale,Montpellier,FranceL10109:10OriginsofPressure-inducedProteinTransitions.TigranV.Chalikian,LeslieDanFacultyofPharmacy,Toronto,CanadaL10209:30SPOTLIGHTLECTURE:HPeffectsonamyloidogenicproteins.JersonSilva,UniversidadeFederaldoRiodeJaneiro,RiodeJaneiro,BrazilL10310:00Break10:30SPOTLIGHTLECTURE:RevealingproteinflexibilityinspinlabelledproteinsusinghighpressureEPR.WayneL.Hubbell,Universityof California,LosAngeles,USAL10411:00Protein-proteininteractions-theeffectsofcosolvents,crowdingandpressure,RolandWinter,TechnischeUniversitätDortmund,GermanyL10511:30EffectsofpressureonthesolubilityandthermodynamicparametersoftetragonallysozymecrystalsTakahisaFujiwara,TheUniversityofTokushima,Japan.L10611:50TET3proteasefromPyrococcushorikoshiirevealsastonishingpropertiesofhighpressureandtemperatureresistanceEvaRosenbaum,LaboratorideLlumdeSincrotró,c/oESRF,FranceL10712:10LunchSession1continuedChair:CatherineRoyerandTigranChalikian13:30AdaptationofcytochromeP450fromapiezophilicbacteriatohighhydrostaticpressuresprovidesacluetothemechanismsofsubstrate-inducedtransitions.ElenaSinevaandDmitriRDavydov,UniversityofCalifornia,SanDiego,USAL10813:50TheVolumesofLigandBindingtoHsp90byHighPressureDenaturation,ZigmantasToleikis,PiotrasCimmperman,andDaumantasMatulis,InstituteofBiotechnology,Vilnius,LithuaniaL10914:10DiscreteStatesofCaseinMicellesprobedbyHighPressureLightScattering,R.Gebhardt,U.KulozikandW.Doster,TechnischeUniversitätMünchen,GermanyL11014:30Useofbiologicaltoolstoinvestigatetheeffectofhigh-pressuretreatmentsonfoodproteincomponents.AmalBenzaria,StéphaneMarchal,MalikaRené-Trouillefou,BertrandCaporiccio,ReinhardLangeandElianeDumay,UniversityofMontpellier,FranceL11114:50Non-enzymaticmodificationsofproteinsunderhighpressuretreatment,UweSchwarzenbolz,ThomasHenle,TechnsicheUniversitätDresden,GermanyL11215:10Breakandposterviewing16:10PackingstateinbilayermembranesofdiacylphosphatidylcholineswithvaryingacylchainlengthsunderhighpressureHitoshiMatsuki,MasakiGoto,NobutakeTamaiandShojiKaneshina,UniversityofTokushima,JapanL113 16:30RheologicalInvestigationsofViscoelasticSubstancesunderHighPressure,L.Kulisiewicz,A.Delgado,C.Rauh,M.Nagel,A.Wierschem,UniversityErlangen-Nürnberg,Germany.L114Session2:SmallMoleculesandHHPChair:RolandWinter16:50Gelatinizationkineticofwaxystarchesunderpressureaccordingtoionicstrength,SimoninH.,GuyonC.,MarzoukiS.,deLamballerieM.,LeBailA.,GEPEA,ONIRISsiteGéraudière,Nantes,FranceL20117:10High-Pressure:atooltoincreasetheproductionofnovelglycosidesHelderVila-Real,AntónioJ.Alfaia,AntónioR.Calado,MariaH.L.Ribeiro,UniversityofLisbon,PortugalL20217:30High-Pressureenhancedactivityandstabilityofa-L-rhamnosidaseandb-D-glucosidaseactivitiesexpressedbynaringinaseimmobilizedontosol-gel@ILmatrices,HelderVila-Real,AntónioJ.Alfaia,PedroGóis,AntónioR.Calado,MariaH.L.Ribeiro,UniversityofLisbon,PortugalL20318:30Dinner20:00VisittotheFreisingCathedral–optionalguidedtourMonday,August30,2010CHAPTER2:HighpressuresensitiveorganismicsystemsSession3:DeepseabiologyChair:FumiyoshiAbeandAbramAertsen08:30KEYNOTELECTURE:Microbialactivityindeepseasediments.PhilM.OgerUniversitédeLyon,EcoleNormaleSupérieuredeLyon,FranceL30109:10Multiplesequenceanalysisrevealshighdiversityofunculturedfungiinthedeep-seasedimentsoftheCentralIndianBasin.SinghP.andRaghukumarC.NationalInstituteofOceanography,Goa,IndiaL30209:30CulturableYeastDiversityfromDeep-seaWatersoftheEquatorialIndianOcean,SamirDamare,VaradaDamare,PankajVerma,ChandralataRaghukumar.NationalInstituteofOceanography,Goa,IndiaL30309:50Pyrococcusyayanosiinov.,thefirststrictpiezophilichyperthermophilicarchaeonisolatedfromadeep-seahydrothermalvent,Mohamed.Jebbar,UniversitédeBretagneOccidentale,Plouzané,FranceL30410:10Breakandposterviewing11:10LearningAboutHighPressure-AdaptedDeep-SeaMicrobesOneCellataTime,DouglasH.Bartlett,ScrippsInstitutionofOceanography, UniversityofCalifornia,SanDiego,LaJolla,USAL30511:40High-throughputscreeningoftheKeioCollectionidentifiesnovelgenesrequiredforgrowthofEscherichiacoliatpressureS.LucasBlack,F.BruceWardandRosalindJ.Allen,UniversityofEdinburgh,EdinburghL30612:00Investigationofusefulpiezophilicmicroorganismsfromdeep-seaenvironments,ChiakiKato,TakayoshiSekiguchi,MakikoEnoki,HaruyukiKanehiro,FuyuItoandShigeruYamanaka,JapanAgencyforMarine-EarthScienceandTechnology,JapanL30712:20LunchSession4:HHP(food)microbiologyChair:DouglasBartlettandPatriciaFernandes13:40SPOTLIGHTLECTURE:Dynamicsofmicrobialmembranesunderhighpressure:astudyusingtime-resolvedfluorescenceanisotropymeasurement,FumiyoshiAbe,JapanAgencyforMarine-EarthScienceandTechnology,JapanL40114:00Theemergence,extentandstabilityofhighpressureresistanceinmesophilicbacteria.DietrichVanlint,NeleRutten,RachaelHazael,EdwardBailey,FilipMeersman,PaulF.McMillan,ChrisW.Michiels,AbramAertsen.KatholiekeUniversiteitLeuven,Belgium.L40214:20EffectofHighHydrostaticPressureonFermentationYeasts,MelbaP.Ortega,LeiZhong,HiromiBaum,XiaoyeGu,MarikoKawamura,AtsushiKobayashi,AkiraYamazaki,andKazutakaYamamoto,NationalFoodResearchInstitute,NARO,JapanL40314:40ComparativeproteomicanalysesofSaccharomycescerevisiaeunderhighhydrostaticpressure,CarolinaD.V.Schuwartz,A.AlbertoR.Fernandes,PatriciaM.B.Fernandes,UniversidadeFederaldoEspíritoSanto,BrasilL40415:00Theroleofproteasomefortheresponseaftersub-lethalhighpressuretreatmentinyeastSaccharomycescerevisae,HitoshiIwahashi,TetsujiHigashi,RandeepRakwal,JunkoShibato,Shin-nichiWakida,NationalInstituteofAdvancedIndustrialScienceandTechnology,JapanL40515:20Analysesofglobalgeneexpressionpatternofdistilleryyeaststrainsubmittedtohighhydrostaticpressuretreatment.Bravim,F.,Lippman,S.,Broach,J.R.,Fernandes,A.A.R.,Fernandes,P.M.B.Universidade FederaldoEspíritoSanto,BrasilL40615:40HP-inactivationkineticsandphenotypicpropertiesofbarosensitiveyeastmutantsobtainedbyUVmutagenesisToruShigematsu,KazukiNomura,YusukeNasuhara,KentaIkarashi,GenNagai,MasaoHirayama,MayumiHayashi,ShigeakiUeno,TomoyukiFujii,NiigataUniversityofPharmacyandAppliedLifeSciences,JapanL40716:00BreakSession4continued:HHP(food)microbiologyChair:ChiakiKato16:30BehaviourofClostridiumbotulinumTypeEendosporesinhighpressuretreatmentsinmodelsystemsversusrealfoods.ChristianLenz,RitaParalta,RudiF.Vogel,TechnischeUniversit?tMünchen,GermanyL40816:50High-pressureassistedthermalinactivationofClostridiumspp.endosporestreatedwithnisinandreutericyclin.SimmonHofstetter,MichaelG.G?nzle,andLynnM.McMullen,UniversityofAlberta,Edmonton,AB,CanadaL40917:10Comparisonoffluorescencebasedmethodsforrapiddetectionofthepressureinducedgerminationofbacterialspores,DanielBaier,KaiReineke,IsabelDoehner,AlexanderMathys,DietrichKnorr,TechnischeUniversit?tBerlin,GermanyL41017:30PressureinducedgerminationofBacillussubtilisspores–Amechanisticstudy,KaiReineke,IsabelD?hner,AlexanderMathys,DietrichKnorr,TechnischeUniversit?tBerlin,GermanyL41118:30Dinner20:00BeerandpostersessionTuesday,August31,2010Session5:HHPeffectsonhumansChair:RolandMeyer-Pittroff08:30KEYNOTELECTURE:TrendsinmolecularandcellularmodelsofHighPressureNeurologicalSyndrome(HPNS),StephenDaniels,PETIC,SchoolofMedicine,CardiffUniversity,UK.L50109:10HighHydrostaticPressureInducesProteinUnfoldingandAggregationinMammalianCellsResultinginTerminalER-stressResponse,Frey,B.,Weiss,E.M.,Schl?tzer-Schrehardt,Meyer-Pittroff,R.,EbelN.,SchlückerE.,FietkauR.,Voll,R.E.,Herrmann,M.,Meister,S.andGaipl,U.S.DpartmentofRadiationOncology,UniversityofErlangen- Nürnberg,GermanyL50209:30HighHydrostaticPressureInactivationofTumorCellsbyPreservingtheirImmunogenicity–GenerationofaWholeCellBasedTumorVaccine,WeissE.M.,JankoC.,MeisterS.,EbelN.,SchlückerE.,Meyer-PittroffR.,FietkauR.,HerrmannM.,GaiplU.S.,FreyB.,DepartmentofRadiationOncology,Friedrich-Alexander-UniversityofErlangen-Nürnberg,GermanyL50309:50BreakCHAPTER3:HighpressuretechnologiesSession6:ProductiveHHP(food)technologiesChair:HorstChristianLangowski10:20KEYNOTELECTURE:Challengesofhighpressurefoodprocesses,VolkerHeinz,DeutschesInstitutfürLebensmitteltechnik,Quakenbrück,GermanyL60111:00Processoptimizationandcontrolstrategiesforindustrialandlaboratoryhighpressureprocesses,CorneliaRauh,AntonioDelgado,LehrstuhlfürStr?mungsmechanik,Friedrich-AlexanderUniversit?tErlangen-Nürnberg,GermanyL60211:20PressureAssistedThermalSterilizationofSoup,KidaneShibeshiandMohammedFarid,DepartmentofChemicalandMaterialsEngineering,theUniversityofAuckland,NewZealandL60311:40Superhighpressureeffectsonpropertiesandultrastructureofbeef,JieZheng.KeyLaboratoryofFoodNutritionandSafety,TianjinUniversityofScience&Technology,ChinaL60412:00Lunch13:00ExcursionWednesday,September1,2010Session6:continuedChair:HeleneSimonin08:30PressureandtemperaturestabilityofthemainappleallergenMald1,JuditSomkuti,MilanHouska,LászlóSmeller,Dept.BiophysicsandRadiationBiology,SemmelweisUniversity,Budapest,HungaryL60508:50Effectofk-caseinhydrolysisonthereassociationbehaviourofpressuredecomposedcaseinmicellesMartinHeinrich,RonaldGebhardt,UlrichKulozik,LehrstuhlfürLebensmittelverfahrenstechnikundMolkereitechnologie,TechnischeUniversit?tMünchen,Germany L60609:10High-pressureassistedencapsulationofvitaminD2inre-assembledcaseinmicelles,OrquídeaMenéndez-Aguirre,WolfgangStuetz,TilmanGrune,AnneKessler,JochenWeiss,J?rgHinrichs,AnimalFoodstuffTechnology,Universit?tHohenheim,GermanyL60709:30NonenzymaticGlycationandDeamidationofFoodProteinsatHighHydrostaticPressure,MarkusBrunnbauer,PeterKoehler,GermanResearchCentreforFoodChemistry,GermanyL60809:50NormalandWaxyCornStarchesTreatedwithHighHydrostaticPressure,KazutakaYamamoto,KenFukami,TamaoHatta,HajimeTaniguchi,andKiyoshiKawai,NationalFoodResearchInstitute,NARO,JapanL60910:10BreakSession6:continuedChair:KazutakaYamamoto10:40Highpressure-inducedstructuraleffectsinplasticpackaging,TobiasRichter,VerenaJost,JuliaSterrandHorst-ChristianLangowski,LehrstuhlfuerLebensmittelverpackungstechnik,TechnischeUniversit?tMünchen,GermanyL61011:00PH-sensitiveCoatingsforIn-SituOpticalMeasurementDuringHigh-PressureTreatmentofFood,M.Nagel,A.Jurchela,C.Rauh,A.WierschemandA.Delgado,Instituteoffluidmechanics,Friedrich-AlexanderUniversityofErlangen-Nuremberg,GermanyL611Session7:AnalyticalHHPtechnologies11:20Amulti-purposemodularsystemforhigh-resolutionmicroscopyathighhydrostaticpressureHughVass,S.LucasBlack,EvaHerzig,PaulClegg,F.BruceWardandRosalindJ.Allen,SUPASchoolofPhysicsandAstronomy,UniversityofEdinburgh,UKL70111:40Farewell弗赖辛介绍　　弗赖辛（Freising）是德国巴伐利亚州弗赖辛县的首府，人口为48,400。城市位于慕尼黑以北的伊萨尔河畔，与慕尼黑国际机场相邻。来往机场的人都可以看到弗赖辛的两座著名山峰---一为主教城堡坐落的教堂山，一为世界上最古老的酿酒坊坐落的魏恩施蒂芬山。　　历史　　 虽然考古发现认为弗赖辛从铜器时代就开始有人定居了，但是并没有发现相关的证据。有据可查的历史始于8世纪，弗赖辛教区的先驱---圣徒Corbinian居住的神殿早大724年就已存在了。根据主教Arbeo整理的Corbinian的传记所记载，Corbinian是由一头熊驮着他的行李翻越阿尔卑斯山的，如今，驮着行李的熊的图案已成为弗赖辛市徽的一部分。虽然教区的教座已在1821年就搬到慕尼黑去了，但直到今天弗赖辛仍然是教区行政部门所在地。　　主教Arbeo于764年-783年在修道院里建造了图书馆和缮写室，于是弗赖辛开始逐渐成为宗教中心。　　996年，费赖辛从奥托三世获得了城市权利。但是，在1150年左右慕尼黑建城之后，弗赖辛就逐渐丧失了其重要的经济地位。　　文化意义　　弗赖辛是巴伐利亚州最古老的人类定居点，在中世纪早期成为巴伐利亚主要的宗教中心，现在也仍是重要的主教教区中心。一些重要的历史文献就是在900年至1200年此地的修道院编写的。